Lozam Lorazepam

Lorazepam: Instructions for Use 

Generic Lorazepam 1 mg is a tranquilizer of the group of benzodiazepine derivatives. It has anxiolytic, muscle relaxant, anticonvulsant and hypnotic effects. It has a sedative effect, relieves psycho-emotional tension, reduces anxiety, fear, and restlessness.

Indications for use of anxiolytics:

• anxiety and panic states;
• depressive disorder accompanied by severe anxiety;
• neurosis;
• management of anxiety with autonomic manifestations;
• insomnia;
• relief of symptoms of alcohol withdrawal: acute agitation, tremor, threatening delirium;
• convulsive seizures, including those caused by epilepsy;
• weakening of spasms in degenerative diseases.

The drug has also found use in anesthesiology. Lorazepam is used for premedication before surgery and other painful procedures to produce a sedative effect and eliminate feelings of fear.

Although you can buy Lorazepam in many pharmacies, keep in mind that the drug is highly addictive, so it requires monitoring when taken over a long period of time.

How long does Lorazepam work?

After ingestion, the drug is quickly absorbed from the gastrointestinal tract. The bioavailability is 90%. Accumulation of maximum plasma concentration is reached after 1-3 hours.

It is metabolized in the liver mainly by oxidation into active and inactive metabolites, which ensure the duration of action of the drug. 

Addiction to Lorazepam

Before you buy Lorazepam online, read the information carefully. The drug can lead to addiction.

The risk of addiction to Lorazepam increases as the dose and duration of use increases, as well as, in patients with alcoholism, drug addiction, personality disorders, phobias, and severe depression.

Signs of Lorazepam addiction:

• changes in behavior;
• the appearance of euphoria;
• sudden mood swings;
• erratic blood pressure, tachycardia;
• pale skin;
• an unsteady, unsteady gait;
• decreased appetite;
• trembling hands and feet;
• unexplained aggression;
• indifference, apathy.

A characteristic sign of habituation is disturbance of sleep-wake rhythm with night awakenings and difficulty falling asleep.

The drug is available with a doctor's prescription. Our pharmacy offers to buy Lorazepam online together with a doctor's prescription. It is very convenient because the cost of Lorazepam includes a prescription, and you will save time by ordering the drug on our website.

Contraindications

Despite the effectiveness of the drug, Lorazepam is contraindicated for these conditions:

• Hypersensitivity to 1,4-benzodiazepine derivatives or any substance in the drug
• Severe respiratory failure, regardless of cause;
• Severe hepatic or renal impairment;
• Myasthenia gravis;
• Glaucoma;
• Acute porphyria;
• Alcohol poisoning;
• Nocturnal apnea syndrome;
• Children under 12 years of age;
• It’s not recommended to use Lorazepam in patients with psychosis;
• Due to its lactose content, the drug should not be used in patients with hereditary lactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption.

No alcoholic beverages should be consumed during treatment with Lorazepam and for 3 days after its completion.

Lorazepam for sleep

Lorazepam is an anxiolytic that is suitable for treating insomnia and anxiety. Nocturnal tranquilizers have the additional sleeping effect that Lorazepam has. However, it must be kept in mind that treatment with benzodiazepines should be limited in time and as short as possible.

Tranquilizers are needed to normalize sleep in neurotic, including anxiety, depressive disorders. Lorazepam can be purchased online in our pharmacy if your doctor has diagnosed one of the overdose conditions.

How long does Lorazepam stay in your system?

The elimination half-life is 6 to 24 hours. Lorazepam and its metabolites are excreted mostly by the kidneys with the urine, a small portion through the intestines.

Lorazepam and alcohol

According to the instructions, the combined use of alcoholic beverages and Lorazepam is strictly contraindicated. This is explained by the fact that alcohol and Lorazepam can affect the brain and nervous system, so this combination can be dangerous.

Drinking alcohol produces a state of euphoria, which is soon replaced by depression, and Lorazepam has the same effect. Thus, when using alcohol and tranquilizers, which reinforce each other's sedative effect, it is possible to fall into a state of deep sleep, from which it is very difficult to come out on your own.

Also under the influence of alcohol the ability of the drug to cause muscle relaxation increases, and the work of the heart and respiratory organs becomes depressed. Such a condition is life-threatening.

After co-administration of alcohol and Lorazepam, it is necessary to call an ambulance immediately. An attempt may be made to induce vomiting in the victim. If consciousness is not impaired, activated charcoal should be taken as directed.

After admission to the hospital, the patient will need gastric lavage and infusion of solutions for infusion, which increase urine excretion. Such actions will help to eliminate the medication from the body. As symptomatic therapy, the antidote, Flumazenil, may be administered.

Dosage of Lorazepam for anxiety

The recommended initial dose for anxiety states is 0.5 to 3 mg per day in several doses taken orally, regardless of meals. This dose may be increased or decreased depending on the needs or age of the patient and at the discretion of the physician. You should not buy Lorazepam online unless advised by your doctor. 

Mechanism of Action

Lorazepam acts on benzodiazepine receptors by increasing the sensitivity of GABA receptors to gamma-aminobutyric acid. Chlorine channels begin to open more frequently, the entrance of chlorine ions into the cells increases and, as a consequence, there is hyperpolarization of the membranes.

This decreases the excitability of neurons and inhibits their activity. The rate of nerve impulse transmission decreases. As a result, inhibition processes increase in the limbic system, which leads to an anxiolytic effect.

The effects of Lorazepam on the body are as follows:

• Reduction of anxiety levels.
• Reduction of feelings of fear, anxiety, tension, emotional excitability, intensity of experiences, increased irritability.
• Facilitation of falling asleep and improving the quality of sleep.
• Elimination of muscle spasms and tension in the muscles.
• Cramps and involuntary muscle contractions.
• Stabilization of the functions of the autonomic nervous system.
• Amnestic action (when administered intravenously).
• Antiemetic effect.

After taking the tranquilizer, there is activity, a burst of energy, a pleasant feeling of relaxation, calmness, mental and physical comfort.

Does Lorazepam cause drowsiness?

Lorazepam reduces anxiety and calms, thereby eliminating insomnia. The drug helps you fall asleep quickly and deeply, but the sleep itself is not very restorative.

Lorazepam overdose

Read the instructions for Lorazepam online and do not exceed the recommended dosage.

Symptoms of overdose: drowsiness, disorientation, slurred speech, and in severe cases, loss of consciousness, coma. 

Treatment: in case of Lorazepam overdose it is necessary to take measures aimed at early excretion of the drug not yet absorbed from the body or reducing its absorption from the digestive tract (inducing vomiting, administration of activated charcoal, gastric lavage – if consciousness is preserved), monitor basic vital functions (respiration, pulse, blood pressure) and if necessary apply an appropriate symptomatic treatment. The specific antidote is Flumazenil.

Does Lorazepam cause nausea?

Lorazepam may cause gastrointestinal side effects: nausea, vomiting, diarrhea or constipation.

You should not withdraw from the treatment with Lorazepam if these side effects occur at the start of therapy, and they soon go away on their own.

If these side effects are significant, it is permissible to take medication temporarily to alleviate the condition. For example, in the case of severe nausea, a one-time symptomatic administration of Cerucal is possible, after consultation and approval by the doctor.

Lorazepam for depression

Lorazepam should only be used on a temporary and short-term basis in the treatment of sleep disorders related to anxiety. Prolonged use of Lorazepam can lead to mental and physical dependence. 

Lorazepam is not an antidepressant. In case of depression, other active agents are used, and Lorazepam can only be used as an adjunctive agent strictly on the doctor's recommendation. 

What is the cost of Lorazepam?

In our online pharmacy, you can buy Lorazepam at an affordable price with a prescription from a doctor. You will always find out the cost of Lorazepam, availability, and basic information on the website.